Gene

Chaf1b

Species
Mus musculus
Symbol
Chaf1b
Name
chromatin assembly factor 1, subunit B
Synonyms
  • 2600017H24Rik
  • C76145
Biotype
protein coding gene
Automated Description
Predicted to be involved in DNA replication-dependent chromatin assembly and nucleosome assembly. Predicted to be located in chromatin and nucleoplasm. Predicted to be part of CAF-1 complex. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human CHAF1B (chromatin assembly factor 1 subunit B).
MGI Description
PHENOTYPE: Mice homozygous for a conditional allele activated in hematopoietic cells exhibit premature death, pancytopenia, reduced bone amrrow and hematopoietic stem cells, and reduced hematopoietic reconstitution. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR15271
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
93.682M93.684M93.686M93.688M93.690M93.692M93.694M93.696M93.698M93.700M93.702M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions