Acts upstream of or within positive regulation of lipopolysaccharide-mediated signaling pathway. Predicted to be located in extracellular region. Is expressed in cerebral cortex; genitourinary system; and lower leg bone. Orthologous to human LY86 (lymphocyte antigen 86).
MGI Description
PHENOTYPE: Mice homozygous for a knock-out allele display impaired LPS-induced B-cell proliferation and antibody production. [provided by MGI curators]