Version: 8.0.0Date: Tue Jan 28 2025
Gene
Cyth2
- Species
- Mus musculus
- Symbol
- Cyth2
- Name
- cytohesin 2
- Synonyms
- Arno
- ARNO
- Biotype
- protein coding gene
- Automated Description
- Enables guanyl-nucleotide exchange factor activity and inositol 1,4,5 trisphosphate binding activity. Predicted to be involved in negative regulation of dendrite development. Predicted to act upstream of or within regulation of cell adhesion. Located in bicellular tight junction. Is active in glutamatergic synapse and postsynapse. Is expressed in brain and spinal cord. Orthologous to human CYTH2 (cytohesin 2).
- MGI Description
- PHENOTYPE: Mice homozygous for a conditional allele activated in Schwann cell exhibit reduced sciatic nerve myelin sheath thickness. Mice homozygous for a null allele exhibit reduced eosinophilic infiltration into the septum an ovalbumin-induced model of murine rhinitis. [provided by MGI curators]
- Cross References
- Additional Information
- Literature
Orthology
- Gene tree
- PANTHER:PTHR10663
Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse
Disease Associations
Cases where the expected disease association was NOT found
Cell color indicative of annotation volume
Sequence Feature Viewer
- Genome location
- Chr7:45456058...45463857 - (7.80 kb)
- Assembly version
- GRCm39
- Viewer Help
Data currently unavailable; sequence viewer under construction