sialyltransferase 7 ((alpha-N-acetylneuraminyl 2,3-betagalactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialyltransferase) C
Siat7c
Biotype
protein coding gene
Automated Description
Predicted to enable alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity. Predicted to be involved in ceramide metabolic process; glycoprotein metabolic process; and oligosaccharide metabolic process. Predicted to be located in nucleoplasm. Is expressed in several structures, including exocrine gland; genitourinary system; hemolymphoid system gland; intestine; and nervous system. Orthologous to human ST6GALNAC3 (ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3).
MGI Description
PHENOTYPE: Mice homozygous for a null allele exhibit no abnormal phenotype. Double homozygotes lacking St6galnac3 and St6galnac4 exhibit lymph node hemorrhage associated with structural disruption of high endothelial venule. [provided by MGI curators]