Gene

Dido1

Species
Mus musculus
Symbol
Dido1
Name
death inducer-obliterator 1
Synonyms
  • 6720461J16Rik
  • C130092D22Rik
Biotype
protein coding gene
Automated Description
Predicted to enable metal ion binding activity. Acts upstream of or within apoptotic signaling pathway. Located in nucleus. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; limb; and spleen. Used to study myelodysplastic/myeloproliferative neoplasm. Orthologous to human DIDO1 (death inducer-obliterator 1).
MGI Description
PHENOTYPE: Mice homozygous for a knock-out allele exhibit severely reduced fertility; about one-half develop a transplantable disease characterized by anomalies in spleen, bone marrow, and peripheral blood and including anemia and various symptoms typical of myeloid dysplasia or myeloid proliferation. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11477
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
180.300M180.305M180.310M180.315M180.320M180.325M180.330M180.335M180.340M180.345M180.350M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions