Gene

Tenm1

Species
Mus musculus
Symbol
Tenm1
Name
teneurin transmembrane protein 1
Synonyms
  • odd Oz/ten-m homolog 1 (Drosophila)
  • Odz1
Biotype
protein coding gene
Automated Description
Enables protein heterodimerization activity and protein homodimerization activity. Involved in positive regulation of cellular component biogenesis; positive regulation of protein phosphorylation; and regulation of transcription by RNA polymerase III. Located in several cellular components, including extracellular region; nucleus; and perinuclear region of cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human TENM1 (teneurin transmembrane protein 1).
MGI Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11219
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
Tenm41286076627 of 9 
Tenm22279874567 of 9 
Tenm33257778607 of 9 

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
Phenotype Term
Annotation details
References
decreased exploration in new environment
decreased hematocrit
decreased mean corpuscular hemoglobin
decreased mean corpuscular volume
increased circulating alanine transaminase level
increased mean corpuscular hemoglobin concentration
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Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Transgenic Alleles

No data available

Models

Model name
Experimental condition
Associated Human Diseases
Associated Phenotypes
Modifier
Source
Tenm1em1(IMPC)Tcp/Tenm1em1(IMPC)Tcp [background:] C57BL/6NCrl-Tenm1em1(IMPC)Tcp/Tcp
  • decreased hematocrit
  • decreased mean corpuscular volume
MGI
Tenm1em1(IMPC)Tcp/Y [background:] C57BL/6NCrl-Tenm1em1(IMPC)Tcp/Tcp
  • decreased exploration in new environment
  • decreased mean corpuscular hemoglobin
MGI
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Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
41.7M41.8M41.9M42.0M42.1M42.2M42.3M42.4M42.5M

Sequence Details

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Expression

Primary Sources
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

7 interactor genes based on 8 annotations
Tenm1 molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
Adgrl1Mus musculus
protein
  • anti tag coimmunoprecipitation
PMID:30774623
protein
Adgrl1Mus musculus
protein
  • confocal microscopy
PMID:30774623
protein
Cntnap2Mus musculus
protein
  • proximity labelling technology
PMID:36417873
protein
Garem2Mus musculus
protein
  • biochemical
PMID:32325033
protein
MetMus musculus
protein
  • proximity labelling technology
PMID:36417873
protein
Stxbp1Mus musculus
protein
  • proximity labelling technology
PMID:36417873
protein
Tenm4Mus musculus
protein
  • biochemical
PMID:32325033
protein
TncMus musculus
protein
  • biochemical
PMID:32325033
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Genetic Interactions

No data available