Version: 8.0.0Date: Tue Jan 28 2025
Gene
Homer1
- Species
- Mus musculus
- Symbol
- Homer1
- Name
- homer scaffolding protein 1
- Synonyms
- HOMER1F
- PSD-Zip45
- Biotype
- protein coding gene
- Automated Description
- Predicted to enable several functions, including scaffold protein binding activity; transmembrane transporter binding activity; and type 5 metabotropic glutamate receptor binding activity. Predicted to be a structural constituent of postsynapse. Involved in regulation of monoatomic ion transport and regulation of postsynaptic neurotransmitter receptor activity. Acts upstream of or within several processes, including behavioral response to cocaine; skeletal muscle contraction; and skeletal muscle fiber development. Located in several cellular components, including apical part of cell; myofibril; and postsynapse. Is active in glutamatergic synapse; postsynaptic cytosol; and postsynaptic density. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human HOMER1 (homer scaffold protein 1).
- MGI Description
- PHENOTYPE: Homozygous mutants exhibit an increase in spontaneous calcium influx in pancreatic acinar cells. Mice homozygous for a knock-out allele exhibit decreased response to formalin-induced pain. [provided by MGI curators]
- Cross References
- Additional Information
- Literature
Orthology
- Gene tree
- PANTHER:PTHR10918
Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse
Disease Associations
Cases where the expected disease association was NOT found
Cell color indicative of annotation volume
Sequence Feature Viewer
- Genome location
- Chr13:93436143...93541637 + (105.49 kb)
- Assembly version
- GRCm39
- Viewer Help
Data currently unavailable; sequence viewer under construction