Gene

Atp1a4

Species
Mus musculus
Symbol
Atp1a4
Name
ATPase, Na+/K+ transporting, alpha 4 polypeptide
Synonyms
None
Biotype
protein coding gene
Automated Description
Enables P-type sodium:potassium-exchanging transporter activity. Acts upstream of or within several processes, including flagellated sperm motility; sodium ion transport; and spermatogenesis. Predicted to be located in rod photoreceptor outer segment and sperm midpiece. Predicted to be part of sodium:potassium-exchanging ATPase complex. Predicted to be active in cell projection and plasma membrane. Is expressed in choroid plexus; epididymis; and testis. Orthologous to human ATP1A4 (ATPase Na+/K+ transporting subunit alpha 4).
MGI Description
PHENOTYPE: Male mice homozygous for a knock-out allele exhibit infertility associated with asthenozoospermia and teratozoospermia. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR43294
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
172.055M172.060M172.065M172.070M172.075M172.080M172.085M

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions