Gene

Tmod3

Species
Mus musculus
Symbol
Tmod3
Name
tropomodulin 3
Synonyms
  • U-Tmod
  • ubiquitous tropomodulin
Biotype
protein coding gene
Automated Description
Enables tropomyosin binding activity. Acts upstream of or within actin cytoskeleton organization; erythrocyte development; and positive regulation of mitotic cell cycle phase transition. Located in striated muscle thin filament. Is expressed in several structures, including alimentary system; brain; heart; metanephros; and sensory organ. Orthologous to human TMOD3 (tropomodulin 3).
MGI Description
PHENOTYPE: Mice homozygous for a gene trap allele exhibit lethality during fetal development with anemia due to impaired erythroid terminal differentiation in the fetal liver. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10901
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
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      Alleles and Variants

      Allele/Variant Symbol
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      Variant
      Variant type
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
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          Models

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            Sequence Feature Viewer

            Genome location
            Assembly version
            GRCm39
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            75.41M75.42M75.43M75.44M75.45M75.46M

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            Tmod3 molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
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              Genetic Interactions

              Tmod3 role
              Tmod3 genetic perturbation
              Interactor gene
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