Version: 8.0.0Date: Tue Jan 28 2025
Gene
Rab25
- Species
- Mus musculus
- Symbol
- Rab25
- Name
- RAB25, member RAS oncogene family
- Synonyms
- AV012978
- expressed sequence AV012978
- Biotype
- protein coding gene
- Automated Description
- Predicted to enable GTP binding activity; GTPase activity; and myosin V binding activity. Involved in epithelial cell morphogenesis. Predicted to be located in cytoplasmic vesicle; plasma membrane; and pseudopodium. Predicted to be active in Golgi apparatus and recycling endosome. Is expressed in gut; nasal cavity epithelium; skin; submandibular gland primordium; and urinary system. Orthologous to human RAB25 (RAB25, member RAS oncogene family).
- MGI Description
- PHENOTYPE: On a 129 background, virgin female homozygotes older than 10 months of age develop vaginal cancer while both male and female homozygotes develop distal esophageal stricture due to squamous cell hyperplasia. [provided by MGI curators]
- Cross References
- Additional Information
- Literature
Orthology
- Gene tree
- PANTHER:PTHR47979
Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse
Disease Associations
Cases where the expected disease association was NOT found
Cell color indicative of annotation volume
Gene | Association | Disease Qualifier | Disease | Evidence | Source | Based On | References |
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Sequence Feature Viewer
- Genome location
- Chr3:88449335...88455586 - (6.25 kb)
- Assembly version
- GRCm39
- Viewer Help
Data currently unavailable; sequence viewer under construction