Gene

Copg1

Species
Mus musculus
Symbol
Copg1
Name
coatomer protein complex, subunit gamma 1
Synonyms
  • AU019265
  • BC056168
Biotype
protein coding gene
Automated Description
Predicted to enable structural molecule activity. Predicted to be involved in several processes, including Golgi vesicle transport; establishment of Golgi localization; and organelle transport along microtubule. Located in Golgi membrane. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Used to study combined immunodeficiency and polyclonal hypergammaglobulinemia. Orthologous to human COPG1 (COPI coat complex subunit gamma 1).
MGI Description
PHENOTYPE: Homozygosity for the p.K652E mutation increases ER stress in B cells and impairs immune response to bacterial infections, leading to weight loss, hunched posture and ruffled fur. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10261
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
87.865M87.870M87.875M87.880M87.885M87.890M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions