Version: 8.0.0
Date: Tue Jan 28 2025
Vamp4
Mus musculusMGI:1858730
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Vamp4

Species
Mus musculus
Symbol
Vamp4
Name
vesicle-associated membrane protein 4
Synonyms
  • D1Ertd147e
  • DNA segment, Chr 1, ERATO Doi 147, expressed
Biotype
protein coding gene
Automated Description
Acts upstream of or within Golgi to plasma membrane protein transport; cellular response to type II interferon; and regulation of Golgi to plasma membrane protein transport. Located in phagocytic vesicle and trans-Golgi network. Part of SNARE complex. Is active in presynaptic endosome membrane. Is expressed in cerebellum layer; gonad; and ventral tegmental area. Orthologous to human VAMP4 (vesicle associated membrane protein 4).
MGI Description
PHENOTYPE: Mice homozygous for a null allele display increased insulin in pancreas beta cells and improved glucose tolerance. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR46897
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
    Association
    Disease Qualifier
    Disease
    Evidence
    Source
    Based On
    References
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
      Molecular consequence
      Has Disease Annotations
      Has Phenotype Annotations
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        Download all Alleles/Variants for all genes of the species

        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
        Has Disease Annotations
        Has Phenotype Annotations
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          Models

          Model name
          Experimental condition
          Associated Human Diseases
          Associated Phenotypes
          Modifier
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            Sequence Feature Viewer

            Genome location
            Assembly version
            GRCm39
            Viewer Help
            162.400M162.405M162.410M162.415M162.420M162.425M

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            Vamp4 molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
            Detection methods
            Source
            Reference
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              Genetic Interactions

              Vamp4 role
              Vamp4 genetic perturbation
              Interactor gene
              Interactor species
              Interactor role
              Interactor genetic perturbation
              Interaction type
              Phenotype or trait
              Source
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