Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including defense response to protozoan; hemopoiesis; and positive regulation of macromolecule biosynthetic process. Located in cytoplasm and nucleus. Is expressed in bladder; central nervous system; and testis. Orthologous to human BATF (basic leucine zipper ATF-like transcription factor).
MGI Description
PHENOTYPE: Homozygote null mice are defective in generation of Th17 T cells. [provided by MGI curators]