Gene

Syt7

Species
Mus musculus
Symbol
Syt7
Name
synaptotagmin VII
Synonyms
  • AI851541
  • B230112P13Rik
Biotype
protein coding gene
Automated Description
Enables SNARE binding activity; calmodulin binding activity; and phospholipid binding activity. Involved in several processes, including calcium ion regulated lysosome exocytosis; regulation of secretion by cell; and synaptic vesicle cycle. Acts upstream of or within plasma membrane repair. Located in several cellular components, including cytoplasmic vesicle; neuronal cell body; and presynaptic membrane. Is active in GABA-ergic synapse and glutamatergic synapse. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human SYT7 (synaptotagmin 7).
MGI Description
PHENOTYPE: Mice homozygous for disruptions in this gene have no gross abnormalities or obvious neurological defects. They do develop fibrosis in the skin and skeletal muscle over time. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10024
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
Phenotype Term
Annotation details
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
    Association
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
      Molecular consequence
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
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          Models

          Model name
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          Associated Human Diseases
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            Sequence Feature Viewer

            Genome location
            Assembly version
            GRCm39
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            10.37M10.38M10.39M10.40M10.41M10.42M10.43M

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            Syt7 molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
            Detection methods
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              Genetic Interactions

              Syt7 role
              Syt7 genetic perturbation
              Interactor gene
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              Interactor role
              Interactor genetic perturbation
              Interaction type
              Phenotype or trait
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