gamma-aminobutyric acid type A receptor subunit theta
Synonyms
None
Biotype
protein coding gene
Automated Description
Predicted to enable GABA-A receptor activity and GABA-gated chloride ion channel activity. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to act upstream of or within chloride transport and gamma-aminobutyric acid signaling pathway. Predicted to be located in plasma membrane. Predicted to be part of GABA-A receptor complex. Is expressed in several structures, including brain; eye; genitourinary system; immune system; and liver and biliary system. Orthologous to human GABRQ (gamma-aminobutyric acid type A receptor subunit theta).
MGI Description
PHENOTYPE: Males hemizygous for a mutation in this gene exhibit decreased prepulse inhibition. [provided by MGI curators]