Predicted to enable hormone activity. Acts upstream of or within response to bacterium. Located in extracellular region. Is expressed in several structures, including brown fat; genitourinary system; intestine; liver; and spleen. Orthologous to human RETNLB (resistin like beta).
MGI Description
PHENOTYPE: Homozygous mutation of this gene on a C57BL/6 background provides protection from DSS-induced colitis while on an FVB/N background, mice are more susceptible to AOM/DSS-induced colon tumors.
[provided by MGI curators]