solute carrier organic anion transporter family, member 1c1
Synonyms
BAST1
Bsat1
Biotype
protein coding gene
Automated Description
Predicted to enable bile acid transmembrane transporter activity; sodium-independent organic anion transmembrane transporter activity; and thyroid hormone transmembrane transporter activity. Predicted to be involved in several processes, including positive regulation of thyroid hormone generation; sodium-independent organic anion transport; and thyroid hormone transport. Located in basolateral plasma membrane. Is expressed in blood vessel; central nervous system; cochlea; and retina. Orthologous to human SLCO1C1 (solute carrier organic anion transporter family member 1C1).
MGI Description
PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased thyroxine and triiodothyronine levels in the forebrain, in the absence of overt growth, reproductive or neurological abnormalities. [provided by MGI curators]