Enables transcription corepressor activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in replication fork. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and integumental system. Orthologous to human DMAP1 (DNA methyltransferase 1 associated protein 1).
MGI Description
PHENOTYPE: Mice homozygous for a knock-out allele die prior to implantation with no 8-cell embryos detected. [provided by MGI curators]