Gene

Aste1

Species
Mus musculus
Symbol
Aste1
Name
asteroid homolog 1
Synonyms
  • 1100001A21Rik
  • AV006403
Biotype
protein coding gene
Automated Description
Predicted to enable 3' overhang single-stranded DNA endodeoxyribonuclease activity. Involved in double-strand break repair via homologous recombination and double-strand break repair via nonhomologous end joining. Is expressed in brain. Human ortholog(s) of this gene implicated in Lynch syndrome and mismatch repair cancer syndrome. Orthologous to human ASTE1 (asteroid homolog 1).
MGI Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR15665
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
Data currently unavailable; sequence viewer under construction

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions