Gene

Uba5

Species
Mus musculus
Symbol
Uba5
Name
ubiquitin-like modifier activating enzyme 5
Synonyms
  • 5730525G14Rik
  • AW240750
Biotype
protein coding gene
Automated Description
Enables UFM1 activating enzyme activity. Involved in myeloid cell differentiation; protein ufmylation; and regulation of type II interferon production. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in cytosol. Is expressed in liver. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 24 and developmental and epileptic encephalopathy 44. Orthologous to human UBA5 (ubiquitin like modifier activating enzyme 5).
MGI Description
PHENOTYPE: Mice homozygous for a knock-out allele die at E12.5. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10953
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
103.924M103.926M103.928M103.930M103.932M103.934M103.936M103.938M103.940M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions