Gene

Mmd

Species
Mus musculus
Symbol
Mmd
Name
monocyte to macrophage differentiation-associated
Synonyms
  • 1200017E07Rik
  • 1810073C06Rik
Biotype
protein coding gene
Automated Description
Predicted to enable protein kinase activity. Predicted to be involved in positive regulation of neuron differentiation; positive regulation of protein kinase activity; and regulation of protein localization. Predicted to be located in Golgi apparatus. Is expressed in several structures, including alimentary system; cerebral cortex; cranial ganglion; musculoskeletal system; and retina. Orthologous to human MMD (monocyte to macrophage differentiation associated).
MGI Description
PHENOTYPE: Mice homozygous for a null allele exhibit impaired macrophage differentiation, increased macrophage apoptosis, and decreased susceptibility to induced arthritis. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR20855
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
90.145M90.150M90.155M90.160M90.165M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions