Predicted to enable protein kinase activity. Predicted to be involved in positive regulation of neuron differentiation; positive regulation of protein kinase activity; and regulation of protein localization. Predicted to be located in Golgi apparatus. Is expressed in several structures, including alimentary system; cerebral cortex; cranial ganglion; musculoskeletal system; and retina. Orthologous to human MMD (monocyte to macrophage differentiation associated).
MGI Description
PHENOTYPE: Mice homozygous for a null allele exhibit impaired macrophage differentiation, increased macrophage apoptosis, and decreased susceptibility to induced arthritis. [provided by MGI curators]