Gene

Tespa1

Species
Mus musculus
Symbol
Tespa1
Name
thymocyte expressed, positive selection associated 1
Synonyms
  • 5830405N20Rik
  • A430001F24Rik
Biotype
protein coding gene
Automated Description
Enables phospholipase binding activity. Involved in several processes, including COP9 signalosome assembly; positive regulation of T cell differentiation in thymus; and positive regulation of T cell receptor signaling pathway. Acts upstream of or within TCR signalosome assembly. Located in cytoplasm. Part of TCR signalosome. Is expressed in ductus deferens; testis; thymus; and thymus primordium. Orthologous to human TESPA1 (thymocyte expressed, positive selection associated 1).
MGI Description
PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired late thymocyte development. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR17469
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
130.160M130.165M130.170M130.175M130.180M130.185M130.190M130.195M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions