Gene

Nudt12

Species
Mus musculus
Symbol
Nudt12
Name
nudix hydrolase 12
Synonyms
  • 0610016O18Rik
  • nudix (nucleoside diphosphate linked moiety X)-type motif 12
Biotype
protein coding gene
Automated Description
Enables RNA NAD-cap (NMN-forming) hydrolase activity; magnesium ion binding activity; and zinc ion binding activity. Involved in NAD-cap decapping; circadian regulation of gene expression; and mRNA catabolic process. Predicted to be located in cytoplasm and nucleus. Predicted to be active in peroxisome. Is expressed in eye. Orthologous to human NUDT12 (nudix hydrolase 12).
MGI Description
PHENOTYPE: Mice homozygous for a null allele exhibit increased NADH levels and circadian clock transcripts. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR42904
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
59.308M59.310M59.312M59.314M59.316M59.318M59.320M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions