Gene

Bcas2

Species
Mus musculus
Symbol
Bcas2
Name
BCAS2 pre-mRNA processing factor
Synonyms
  • 6430539P16Rik
  • AI132645
Biotype
protein coding gene
Automated Description
Acts upstream of or within several processes, including alternative mRNA splicing, via spliceosome; ovarian follicle development; and spindle assembly. Part of Prp19 complex. Is expressed in several structures, including central nervous system; early conceptus; oocyte; peripheral nervous system ganglion; and submandibular gland primordium. Human ortholog(s) of this gene implicated in breast cancer. Orthologous to human BCAS2 (BCAS2 pre-mRNA processing factor).
MGI Description
PHENOTYPE: Mice homozygous for a knock-out allele exhibit complete lethality. Pups of dams homozygous for a conditional allele activated in oocytes exhibit lethality of pups associated with defects in DNA damage repair and DNA replication. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13296
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
103.079M103.080M103.081M103.082M103.083M103.084M103.085M103.086M

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions