Gene

Map1lc3a

Species
Mus musculus
Symbol
Map1lc3a
Name
microtubule-associated protein 1 light chain 3 alpha
Synonyms
  • 1010001H21Rik
  • 4922501H04Rik
Biotype
protein coding gene
Automated Description
Predicted to enable microtubule binding activity; phosphatidylethanolamine binding activity; and ubiquitin protein ligase binding activity. Predicted to be involved in cellular response to nitrogen starvation; intracellular signaling cassette; and macroautophagy. Predicted to act upstream of or within autophagy of mitochondrion. Located in autophagosome membrane. Is expressed in several structures, including central nervous system; heart; jaw; peripheral nervous system ganglion; and sensory organ. Human ortholog(s) of this gene implicated in glioblastoma. Orthologous to human MAP1LC3A (microtubule associated protein 1 light chain 3 alpha).
MGI Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10969
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
155.1184M155.1186M155.1188M155.1190M155.1192M155.1194M155.1196M155.1198M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions