Acts upstream of or within mitochondrion organization and response to food. Predicted to be located in mitochondrial membrane. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 29. Orthologous to human TMEM126B (transmembrane protein 126B).
MGI Description
PHENOTYPE: Homozygous knockout reduces high-fat diet-induced phenotypes such as obesity and kidney damage. [provided by MGI curators]