Gene

Pcgf3

Species
Mus musculus
Symbol
Pcgf3
Name
polycomb group ring finger 3
Synonyms
  • 2310035N15Rik
  • AI662857
Biotype
protein coding gene
Automated Description
Enables histone H2AK119 ubiquitin ligase activity. Involved in random inactivation of X chromosome. Part of PcG protein complex. Colocalizes with X chromosome. Is expressed in several structures, including branchial arch; central nervous system; limb; otocyst; and urinary system. Orthologous to human PCGF3 (polycomb group ring finger 3).
MGI Description
PHENOTYPE: Mice homozygous for a transgenic gene disruption exhibit limb defects and spleen agenesis. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR45893
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
108.610M108.615M108.620M108.625M108.630M108.635M108.640M108.645M108.650M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions