Version: 8.0.0
Date: Tue Jan 28 2025
Eny2
Mus musculusMGI:1919286
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Eny2

Species
Mus musculus
Symbol
Eny2
Name
ENY2 transcription and export complex 2 subunit
Synonyms
  • 1810057B09Rik
  • RIKEN cDNA 1810057B09 gene
Biotype
protein coding gene
Automated Description
Predicted to enable chromatin binding activity and nuclear receptor coactivator activity. Predicted to be involved in negative regulation of insulin secretion involved in cellular response to glucose stimulus; poly(A)+ mRNA export from nucleus; and regulation of DNA-templated transcription. Predicted to be located in mitochondrion and nucleoplasm. Predicted to be part of SAGA complex and nucleus. Is expressed in midbrain ventricular layer; neural retinal epithelium; olfactory cortex ventricular layer; and telencephalon ventricular layer. Orthologous to human ENY2 (ENY2 transcription and export complex 2 subunit).
MGI Description
PHENOTYPE: Mice homozygous for a knock-out allele show complete embryonic lethality prior to organogenesis. In vitro outgrowth assays show that blastocysts hatch from the zona pellucida but form irregular outgrowths with no inner cell mass colony or trophoblast giant cells after 3 days in culture. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12514
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
      Has Disease Annotations
      Has Phenotype Annotations
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        Models

        Model name
        Experimental condition
        Associated Human Diseases
        Associated Phenotypes
        Modifier
        Source
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          Sequence Feature Viewer

          Genome location
          Assembly version
          GRCm39
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          Data currently unavailable; sequence viewer under construction

          Sequence Details

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          Expression

          Primary Sources
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          Eny2 molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection methods
          Source
          Reference
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            Genetic Interactions

            Eny2 role
            Eny2 genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
            Source
            Reference
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