Predicted to enable several functions, including GTP binding activity; GTPase activity; and kinase inhibitor activity. Involved in T cell differentiation and mast cell activation. Located in cytoplasm and immunological synapse. Is expressed in cranial ganglion; dorsal root ganglion; and sensory organ. Human ortholog(s) of this gene implicated in epidermodysplasia verruciformis. Orthologous to human RHOH (ras homolog family member H).
MGI Description
PHENOTYPE: Mice homozygous for disruptions in this gene display abnormalities in the differentiation of T cells and mast cell physiology. [provided by MGI curators]