Gene

Ct55

Species
Mus musculus
Symbol
Ct55
Name
cancer/testis antigen 55
Synonyms
  • 4930502E18Rik
  • RGD1559599
Biotype
protein coding gene
Automated Description
Involved in spermatogenesis. Located in acrosomal vesicle and sperm flagellum. Human ortholog(s) of this gene implicated in X-linked spermatogenic failure 7. Orthologous to human CT55 (cancer/testis antigen 55).
MGI Description
PHENOTYPE: Mice homozygous for a null allele show reduced susceptibility to weight loss, rectal prolapse and visible tumors in an AOM/DSS model of colitis and tumorogenesis. Mice homozygous for a different null allele show a progressive decline in male fertility along with defects in acrosome development, sperm individualization, excess cytoplasm removal and cumulus-oocyte complex penetration capacity, and an impaired autophagic process during spermatogenesis. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR45418
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
52.728M52.730M52.732M52.734M52.736M52.738M52.740M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions