Gene

Pik3r4

Species
Mus musculus
Symbol
Pik3r4
Name
phosphoinositide-3-kinase regulatory subunit 4
Synonyms
  • 2210010O15Rik
  • C730038E05Rik
Biotype
protein coding gene
Automated Description
Predicted to enable protein serine/threonine kinase activity. Involved in cellular response to glucose starvation. Located in axoneme. Part of phosphatidylinositol 3-kinase complex, class III. Is expressed in central nervous system; embryo; retina inner nuclear layer; retina nuclear layer; and retina outer nuclear layer. Orthologous to human PIK3R4 (phosphoinositide-3-kinase regulatory subunit 4).
MGI Description
PHENOTYPE: Mice homozygous for a knock-out allele exhibit early embryonic lethality before E7.5. Mice homozygous for a conditional allele activated in muscles exhibit symptoms of autophagic vacuolar myopathies. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR17583
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
105.525M105.530M105.535M105.540M105.545M105.550M105.555M105.560M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions