Gene

Zdhhc2

Species
Mus musculus
Symbol
Zdhhc2
Name
zinc finger, DHHC domain containing 2
Synonyms
  • 5730415P04Rik
  • 6430583A19Rik
Biotype
protein coding gene
Automated Description
Enables protein-cysteine S-myristoyltransferase activity; protein-cysteine S-palmitoyltransferase activity; and protein-cysteine S-stearoyltransferase activity. Involved in peptidyl-L-cysteine S-palmitoylation; protein localization to membrane; and synapse assembly. Acts upstream of or within protein palmitoylation. Located in plasma membrane; postsynaptic recycling endosome; and recycling endosome membrane. Is expressed in several structures, including early conceptus; genitourinary system; nervous system; pancreas tip epithelium; and retina. Orthologous to human ZDHHC2 (zinc finger DHHC-type palmitoyltransferase 2).
MGI Description
PHENOTYPE: Mice homozygous for a null allele exhibit decreased susceptibility to imiquimod-induced psoriasis. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR22883
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
40.88M40.89M40.90M40.91M40.92M40.93M40.94M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions