Predicted to enable dTDP-glucose 4,6-dehydratase activity. Predicted to be involved in nucleotide-sugar metabolic process. Is expressed in several structures, including alimentary system; cranium; eye; integumental system; and telencephalon. Human ortholog(s) of this gene implicated in Catel Manzke syndrome. Orthologous to human TGDS (TDP-glucose 4,6-dehydratase).
MGI Description
PHENOTYPE: Mice homozygous for an ENU-induced allele exhibit micrognathia and cleft palate. [provided by MGI curators]