T cell receptor associated transmembrane adaptor 1
Synonyms
C030046M14Rik
RIKEN cDNA C030046M14 gene
Biotype
protein coding gene
Automated Description
Predicted to be involved in negative regulation of receptor recycling and positive regulation of T cell receptor signaling pathway. Predicted to act upstream of or within negative regulation of transport and positive regulation of calcium-mediated signaling. Predicted to be located in centriolar satellite; mitotic spindle; and plasma membrane. Predicted to be part of T cell receptor complex. Orthologous to human TRAT1 (T cell receptor associated transmembrane adaptor 1).
MGI Description
PHENOTYPE: Mice with homozygous disruption of this gene display decreased body weight and a proportional reduction in lymph organ cell numbers; however T and B cell function are normal. [provided by MGI curators]