Gene

Batf3

Species
Mus musculus
Symbol
Batf3
Name
basic leucine zipper transcription factor, ATF-like 3
Synonyms
  • 9130211I03Rik
  • Jdp1
Biotype
protein coding gene
Automated Description
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in myeloid dendritic cell differentiation and response to virus. Predicted to be located in cytosol; nucleolus; and nucleoplasm. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to be active in nucleus. Is expressed in central nervous system and female associated reproductive structure. Orthologous to human BATF3 (basic leucine zipper ATF-like transcription factor 3).
MGI Description
PHENOTYPE: Mice homozygous for a null mutation lack CD8alpha+ dendritic cells, have dysfunctional cross-presentation of antigens, and generate lower numbers of memory CD8+ T cells in response to infection. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23351
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

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Other Sources
Phenotype Term
Annotation details
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
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      Alleles and Variants

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        Transgenic Alleles

        Species
        (carrying the transgene)
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          Models

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            Sequence Feature Viewer

            Genome location
            Assembly version
            GRCm39
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            190.831M190.832M190.833M190.834M190.835M190.836M190.837M190.838M190.839M190.840M190.841M

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            Batf3 molecule type
            Interactor gene
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              Genetic Interactions

              Batf3 role
              Batf3 genetic perturbation
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