Version: 8.0.0
Date: Tue Jan 28 2025
Ddo
Mus musculusMGI:1925528
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Ddo

Species
Mus musculus
Symbol
Ddo
Name
D-aspartate oxidase
Synonyms
  • 5330420D20Rik
  • 5730402C02Rik
Biotype
protein coding gene
Automated Description
Enables D-aspartate oxidase activity and FAD binding activity. Involved in D-amino acid catabolic process; nervous system process; and regulation of cell communication. Acts upstream of or within several processes, including aspartate metabolic process; grooming behavior; and insemination. Predicted to be located in cytosol and peroxisomal matrix. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; chordamesoderm; nervous system; respiratory system; and sensory organ. Orthologous to human DDO (D-aspartate oxidase).
MGI Description
PHENOTYPE: Homozygous null mice are viable and fertile, but can display impaired male copulation, decreased autogrooming, increased body weight, and increased D-aspartate levels, depending on the mutant allele. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11530
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
    Association
    Disease Qualifier
    Disease
    Evidence
    Source
    Based On
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
      Molecular consequence
      Has Disease Annotations
      Has Phenotype Annotations
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
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        Has Phenotype Annotations
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          Models

          Model name
          Experimental condition
          Associated Human Diseases
          Associated Phenotypes
          Modifier
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            Sequence Feature Viewer

            Genome location
            Assembly version
            GRCm39
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            40.510M40.515M40.520M40.525M40.530M40.535M40.540M40.545M40.550M40.555M

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            Ddo molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
            Detection methods
            Source
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              Genetic Interactions

              Ddo role
              Ddo genetic perturbation
              Interactor gene
              Interactor species
              Interactor role
              Interactor genetic perturbation
              Interaction type
              Phenotype or trait
              Source
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