Gene

Fbxo22

Species
Mus musculus
Symbol
Fbxo22
Name
F-box protein 22
Synonyms
  • 0610033L19Rik
  • 1600016C16Rik
Biotype
protein coding gene
Automated Description
Acts upstream of or within several processes, including positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination; and regulation of skeletal muscle fiber development. Located in cytoplasm and nucleus. Orthologous to human FBXO22 (F-box protein 22).
MGI Description
PHENOTYPE: Mice homozygous for one null allele display infertility, decreased grip strength and decreased prepulse inhibition. Mice homozygous for a second null allele display partial lethality and decreased cell proliferation. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR14939
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
55.118M55.120M55.122M55.124M55.126M55.128M55.130M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions