Gene

Itm2c

Species
Mus musculus
Symbol
Itm2c
Name
integral membrane protein 2C
Synonyms
  • 3110038L02Rik
  • AU041202
Biotype
protein coding gene
Automated Description
Enables ATP binding activity. Involved in positive regulation of extrinsic apoptotic signaling pathway. Located in lysosome. Is expressed in several structures, including central nervous system; genitourinary system; and retina. Orthologous to human ITM2C (integral membrane protein 2C).
MGI Description
PHENOTYPE: Mice homozygous for a knock-out allele are viable, fertile and overtly normal with no alterations in the development, maturation and differentiation of B-lymphocytes or production of antibodies by antibody secreting cells. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10962
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
85.824M85.826M85.828M85.830M85.832M85.834M85.836M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions