Version: 8.0.0
Date: Tue Jan 28 2025
Sap30
Mus musculusMGI:1929129
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Sap30

Species
Mus musculus
Symbol
Sap30
Name
sin3 associated polypeptide
Synonyms
  • 30kDa
Biotype
protein coding gene
Automated Description
Predicted to enable transcription corepressor activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II and skeletal muscle cell differentiation. Located in nucleus. Is expressed in several structures, including branchial arch; cerebral cortex; early embryo; limb bud; and sensory organ. Orthologous to human SAP30 (Sin3A associated protein 30).
MGI Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13286
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensSAP309 of 10YesYes☑☑☑☑☑☑☑☑☐☑  
Rattus norvegicusSap309 of 9YesYes☑ ☑☑☑☑☑☑☑☑  
Xenopus tropicalissap308 of 9YesYes☑ ☑☑☑☑☑☑☑☐  
Drosophila melanogasterSap308 of 9YesNo☑ ☑☑☑☑☑☑☐☑  
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
Sap30l121667567 of 9☑☐☑☐☑☑☑☑☑ 

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
Phenotype Term
Annotation details
References
increased circulating glucose level
increased mean corpuscular hemoglobin
increased mean corpuscular volume
preweaning lethality, incomplete penetrance
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Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
Species
Gene
Association
Disease Qualifier
Disease
Evidence
Source
Based On
References
No records match query. Try removing filters.
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    Alleles and Variants

    Genome location
    Assembly version
    GRCm39
    Viewer Help
    Data currently unavailable; sequence viewer under construction
    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
    Sap30em1(IMPC)Jallele
    		Yes
    NC_000074.7:g.57939133T>Cvariant
    SNP
    • intron variant
    NC_000074.7:g.57939410A>Gvariant
    SNP
    • intron variant
    NC_000074.7:g.57939738T>Cvariant
    SNP
    • intron variant
    NC_000074.7:g.57936504A>Gvariant
    SNP
    • intron variant
    NC_000074.7:g.57937073A>Cvariant
    SNP
    • intron variant
    NC_000074.7:g.57939083C>Tvariant
    SNP
    • intron variant
    NC_000074.7:g.57939423C>Tvariant
    SNP
    • intron variant
    NC_000074.7:g.57936284C>Tvariant
    SNP
    • intron variant
    NC_000074.7:g.57936748A>Gvariant
    SNP
    • intron variant
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    View detailed Alleles/Variants information
    Download all Alleles/Variants for all genes of the species

    Transgenic Alleles

    No data available

    Models

    Model name
    Experimental condition
    Associated Human Diseases
    Associated Phenotypes
    Modifier
    Source
    Sap30em1(IMPC)J/Sap30em1(IMPC)J [background:] C57BL/6NJ-Sap30em1(IMPC)J/Mmjax
    • increased circulating glucose level
    • increased mean corpuscular hemoglobin
    		MGI
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    Sequence Feature Viewer

    Genome location
    Assembly version
    GRCm39
    Viewer Help
    Data currently unavailable; sequence viewer under construction

    Sequence Details

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    Expression

    Primary Sources
    Other Sources
    Must provide at least one subject
    Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

    Molecular Interactions

    13 interactor genes based on 21 annotations
    Sap30 molecule type
    Interactor gene
    Interactor species
    Interactor molecule type
    Detection methods
    Source
    Reference
    protein
    		Cir1Mus musculus
    protein
    • biochemical
    		PMID:32325033
    protein
    		Hdac1Mus musculus
    protein
    • coimmunoprecipitation
    		PMID:9702189
    protein
    		Hdac2Mus musculus
    protein
    • coimmunoprecipitation
    		PMID:9702189
    protein
    		Ifrd1Mus musculus
    protein
    • affinity chromatography technology
    		PMID:12198164
    protein
    		Ing1Mus musculus
    protein
    • biochemical
    		PMID:32325033
    protein
    		Ncor1Mus musculus
    protein
    • pull down
    		PMID:9702189
    protein
    		Ncor1Mus musculus
    protein
    • pull down
    		PMID:9702189
    protein
    		Ncor1Mus musculus
    protein
    • pull down
    		PMID:9702189
    protein
    		Ncor2Mus musculus
    protein
    • biochemical
    		PMID:32325033
    protein
    		Rbbp4Mus musculus
    protein
    • coimmunoprecipitation
    		PMID:9702189
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    Genetic Interactions

    No data available