MTOR associated protein, LST8 homolog (S. cerevisiae)
Synonyms
0610033N12Rik
AA409454
Biotype
protein coding gene
Automated Description
Predicted to enable protein serine/threonine kinase activator activity. Acts upstream of or within positive regulation of actin filament polymerization and positive regulation of peptidyl-tyrosine phosphorylation. Part of TORC1 complex. Is expressed in central nervous system and retina. Orthologous to human MLST8 (MTOR associated protein, LST8 homolog).
MGI Description
PHENOTYPE: Mice homozygous for a null mutation exhibit lethality around E10.5 and abnormal yolk sac vasculature, brain development and heart development. [provided by MGI curators]