Gene

Mlst8

Species
Mus musculus
Symbol
Mlst8
Name
MTOR associated protein, LST8 homolog (S. cerevisiae)
Synonyms
  • 0610033N12Rik
  • AA409454
Biotype
protein coding gene
Automated Description
Predicted to enable protein serine/threonine kinase activator activity. Acts upstream of or within positive regulation of actin filament polymerization and positive regulation of peptidyl-tyrosine phosphorylation. Part of TORC1 complex. Is expressed in central nervous system and retina. Orthologous to human MLST8 (MTOR associated protein, LST8 homolog).
MGI Description
PHENOTYPE: Mice homozygous for a null mutation exhibit lethality around E10.5 and abnormal yolk sac vasculature, brain development and heart development. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR19842
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
24.6930M24.6935M24.6940M24.6945M24.6950M24.6955M24.6960M24.6965M24.6970M24.6975M24.6980M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions