Gene

Cript

Species
Mus musculus
Symbol
Cript
Name
cysteine-rich PDZ-binding protein
Synonyms
  • 1200020A08Rik
  • AA589469
Biotype
protein coding gene
Automated Description
Predicted to enable PDZ domain binding activity; microtubule binding activity; and scaffold protein binding activity. Predicted to be involved in several processes, including cytoplasmic microtubule organization; protein localization to microtubule; and regulation of postsynaptic density organization. Predicted to be located in dendrite; neuronal cell body; and postsynaptic density. Predicted to be part of spliceosomal complex. Predicted to be active in dendrite; glutamatergic synapse; and postsynaptic density, intracellular component. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system; nervous system; and retina layer. Human ortholog(s) of this gene implicated in Rothmund-Thomson syndrome. Orthologous to human CRIPT (CXXC repeat containing interactor of PDZ3 domain).
MGI Description
PHENOTYPE: Mice homozygous for a transposon induced allele exhibit embryonic lethality at E8. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11805
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
87.333M87.334M87.335M87.336M87.337M87.338M87.339M87.340M87.341M87.342M87.343M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions