Enables receptor ligand activity; substance K receptor binding activity; and substance P receptor binding activity. Involved in positive regulation of cytosolic calcium ion concentration and tachykinin receptor signaling pathway. Acts upstream of or within positive regulation of saliva secretion. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including adrenal gland; genitourinary system; gut; hemolymphoid system gland; and integumental system. Orthologous to human TAC4 (tachykinin precursor 4).
MGI Description
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased pro-B cells without an increase in mature B cells. [provided by MGI curators]