Gene

Tac4

Species
Mus musculus
Symbol
Tac4
Name
tachykinin 4
Synonyms
  • AW489379
  • expressed sequence AW489379
Biotype
protein coding gene
Automated Description
Enables receptor ligand activity; substance K receptor binding activity; and substance P receptor binding activity. Involved in positive regulation of cytosolic calcium ion concentration and tachykinin receptor signaling pathway. Acts upstream of or within positive regulation of saliva secretion. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including adrenal gland; genitourinary system; gut; hemolymphoid system gland; and integumental system. Orthologous to human TAC4 (tachykinin precursor 4).
MGI Description
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased pro-B cells without an increase in mature B cells. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11250
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
95.153M95.154M95.155M95.156M95.157M95.158M95.159M95.160M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions