Enables GTP binding activity and GTPase activity. Predicted to be involved in several processes, including anterograde axonal protein transport; multivesicular body sorting pathway; and synaptic vesicle endocytosis. Located in Golgi apparatus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Used to study platelet storage pool deficiency. Orthologous to human RAB27B (RAB27B, member RAS oncogene family).
MGI Description
PHENOTYPE: Mice homozygous for one null allele exhibit impaired platelet aggregation. [provided by MGI curators]