Gene

Srcin1

Species
Mus musculus
Symbol
Srcin1
Name
SRC kinase signaling inhibitor 1
Synonyms
  • mKIAA1684
  • P140
Biotype
protein coding gene
Automated Description
Predicted to enable protein domain specific binding activity and protein kinase binding activity. Involved in regulation of synapse assembly. Acts upstream of or within negative regulation of cell adhesion. Located in postsynaptic density. Is active in glutamatergic synapse and presynapse. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and respiratory system. Orthologous to human SRCIN1 (SRC kinase signaling inhibitor 1).
MGI Description
PHENOTYPE: Mice homozygous for a knock-out allele display abnormalities in object recognition memory and motor learning, dendritic spine disorganization, impaired synaptic plasticity, and reduced long term potentiation and long term depression. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR22741
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
97.41M97.42M97.43M97.44M97.45M97.46M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions