Version: 8.0.0
Date: Tue Jan 28 2025
Mmp1b
Mus musculusMGI:1933847
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Mmp1b

Species
Mus musculus
Symbol
Mmp1b
Name
matrix metallopeptidase 1b (interstitial collagenase)
Synonyms
  • Mcol-B
Biotype
protein coding gene
Automated Description
Enables peptidase activity. Predicted to be involved in several processes, including cellular response to UV-A; collagen catabolic process; and extracellular matrix organization. Predicted to be located in extracellular matrix and extracellular region. Is expressed in embryo; placenta; and trophoblast giant cell. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); female reproductive organ cancer (multiple); intrinsic cardiomyopathy (multiple); obstructive lung disease (multiple); and urinary system cancer (multiple). Orthologous to human MMP1 (matrix metallopeptidase 1).
MGI Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10201
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensMMP110 of 10YesYes☑☑☑☑☑☑☑☑☑☑  
Rattus norvegicusMmp1b5 of 9YesYes☑ ☐☐☑☑☐☑☑☐  
Xenopus tropicalismmp13 of 9YesYes☑ ☐☐☐☑☐☑☐☐  
Caenorhabditis eleganszmp-33 of 9YesYes☑ ☐☑☐☐☐☑☐☐  
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
Mmp1a146489829 of 9☑☑☑☑☑☑☑☑☑ 
Mmp3248062457 of 9☑☐☑☐☑☑☑☑☑ 
Mmp10348360447 of 9☑☐☑☐☑☑☑☑☑ 
Mmp8446562457 of 9☑☐☑☐☑☑☑☑☑ 
Mmp27547360457 of 9☑☐☑☐☑☑☑☑☑ 
Mmp13646159447 of 9☑☐☑☐☑☑☑☑☑ 
Mmp2769838286 of 9☑☐☑☐☐☑☑☑☑ 
Mmp20847152397 of 9☑☐☑☐☑☑☑☑☑ 
Mmp12943756417 of 9☑☐☑☐☑☑☑☑☑ 
Mmp241052748356 of 9☑☐☑☐☐☑☑☑☑ 
Mmp151153846336 of 9☑☐☑☐☐☑☑☑☑ 
Mmp141252247336 of 9☑☐☑☐☐☑☑☑☑ 
Mmp161349348356 of 9☑☐☑☐☐☑☑☑☑ 
Mmp91471335245 of 9☑☐☑☐☐☐☑☑☑ 
Mmp251551445326 of 9☑☐☑☐☐☑☑☑☑ 
Mmp171649947326 of 9☑☐☑☐☐☑☑☑☑ 
Mmp191749845336 of 9☑☐☑☐☐☑☑☑☑ 
Mmp281852643286 of 9☑☐☑☐☐☑☑☑☑ 
Mmp111939847356 of 9☑☐☑☐☐☑☑☑☑ 
Mmp212046041283 of 9☑☐☐☐☐☐☑☑☐ 
Mmp72123361437 of 9☑☐☑☐☑☑☑☑☑ 
Mmp232240935232 of 9☑☐☐☐☐☐☑☐☐ 
Hpx2319635232 of 9☑☐☐☐☐☐☐☑☐ 

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
Species
Gene
Association
Disease Qualifier
Disease
Evidence
Source
Based On
References
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    Alleles and Variants

    Genome location
    Assembly version
    GRCm39
    Viewer Help
    Data currently unavailable; sequence viewer under construction
    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
    Mmp1bem1(IMPC)Jallele
    NC_000075.7:g.7377565A>Gvariant
    SNP
    • intron variant
    NC_000075.7:g.7377841T>Cvariant
    SNP
    • intron variant
    NC_000075.7:g.7367919G>Avariant
    SNP
    • intron variant
    NC_000075.7:g.7368874C>Tvariant
    SNP
    • intron variant
    NC_000075.7:g.7369294T>Cvariant
    SNP
    • missense variant
    NC_000075.7:g.7375789A>Tvariant
    SNP
    • intron variant
    NC_000075.7:g.7376216C>Gvariant
    SNP
    • intron variant
    NC_000075.7:g.7376278T>Avariant
    SNP
    • intron variant
    NC_000075.7:g.7376352C>Tvariant
    SNP
    • intron variant
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    Transgenic Alleles

    No data available

    Models

    No data available

    Sequence Feature Viewer

    Genome location
    Assembly version
    GRCm39
    Viewer Help
    Data currently unavailable; sequence viewer under construction

    Sequence Details

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    Expression

    Primary Sources
    Other Sources
    Must provide at least one subject
    Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

    Molecular Interactions

    No data available

    Genetic Interactions

    No data available