Version: 8.0.0
Date: Tue Jan 28 2025
Hapln2
Mus musculusMGI:2137300
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Hapln2

Species
Mus musculus
Symbol
Hapln2
Name
hyaluronan and proteoglycan link protein 2
Synonyms
  • 4930401E20Rik
  • brain link protein 1
Biotype
protein coding gene
Automated Description
Predicted to enable hyaluronic acid binding activity. Acts upstream of or within establishment of blood-nerve barrier and extracellular matrix assembly. Located in extracellular matrix and node of Ranvier. Is expressed in brain. Orthologous to human HAPLN2 (hyaluronan and proteoglycan link protein 2).
MGI Description
PHENOTYPE: Homozygous null mice display reduced nerve conduction velocity and abnormalities in the neuronal extracellular matrix. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR22804
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume
No data available

Alleles and Variants

Download all Alleles/Variants for all genes of the species

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
Data currently unavailable; sequence viewer under construction

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions