Gene

Golga2

Species
Mus musculus
Symbol
Golga2
Name
golgin A2
Synonyms
  • AW555139
  • expressed sequence AW555139
Biotype
protein coding gene
Automated Description
Enables importin-alpha family protein binding activity. Involved in asymmetric cell division and meiotic spindle assembly. Acts upstream of or within Golgi localization and positive regulation of axonogenesis. Located in Golgi apparatus; perinuclear region of cytoplasm; and spindle pole. Is expressed in several structures, including brain; eye; gonad; musculoskeletal system; and unsegmented mesenchyme. Orthologous to human GOLGA2 (golgin A2).
MGI Description
PHENOTYPE: Homozygotes for a null allele show premature death, developmental delay, ataxia, Purkinje neuron loss, and male infertility with globozoospermia and lack of acrosome formation. Homozygotes for a different null allele show partial prenatal lethality and autophagy-induced liver and lung fibrosis. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10881
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
32.180M32.182M32.184M32.186M32.188M32.190M32.192M32.194M32.196M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions