Gene

Clca2

Species
Mus musculus
Symbol
Clca2
Name
chloride channel accessory 2
Synonyms
  • AI586120
  • chloride channel calcium activated 5
Biotype
protein coding gene
Automated Description
Enables chloride channel activity and ligand-gated monoatomic ion channel activity. Acts upstream of or within chloride transport. Located in plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; immune system; skin; and telencephalon. Orthologous to human CLCA2 (chloride channel accessory 2).
MGI Description
PHENOTYPE: Mice homozygous for a targeted null mutation exhibit increases in liver weight to body weight ratio and hepatocyte hypertrophy; one incidence of multifocal hepatic necrosis. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10579
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
144.780M144.785M144.790M144.795M144.800M144.805M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions