Gene

Hsd17b13

Species
Mus musculus
Symbol
Hsd17b13
Name
hydroxysteroid (17-beta) dehydrogenase 13
Synonyms
  • AI047820
  • expressed sequence AI047820
Biotype
protein coding gene
Automated Description
Predicted to enable oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor and steroid dehydrogenase activity. Predicted to be involved in lipid metabolic process. Predicted to act upstream of or within positive regulation of lipid biosynthetic process. Located in lipid droplet. Orthologous to human HSD17B13 (hydroxysteroid 17-beta dehydrogenase 13).
MGI Description
PHENOTYPE: Male mice homozygous for a null allele exhibit hepatic steatosis, increased liver triglyceride levels, increased lipogenesis, decreased fatty acid beta-oxidaton, and liver inflammation. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24322
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
104.104M104.106M104.108M104.110M104.112M104.114M104.116M104.118M104.120M104.122M104.124M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions