Enables plasmanylethanolamine desaturase activity. Involved in ether lipid biosynthetic process. Located in endoplasmic reticulum membrane. Orthologous to several human genes including PEDS1 (plasmanylethanolamine desaturase 1).
MGI Description
PHENOTYPE: Mice homozygous for a knock-out allele lack plasmanylethanolamine desaturase activity and show decreased body weight and severely reduced plasmalogen levels in all analyzed tissues. [provided by MGI curators]